The inside of Patrick Gildea’s new salon.Patrick Gildea Hairdressing is delighted to have triumphed in the JCI Friendly BusinessAwards under the category for shop layout and design. The impressive new salon was announced as the winner at Monday night’s award ceremony in Letterkenny.Style Director and Team Leader Noreen Gallagher, who has been working with Patrick Gildea Hairdressing for twenty years, collected the award on behalf of the company. Commenting on their award success Noreen stated “I am delighted to accept this award on behalf of Patrick Gildea Hairdressing.“We are absolutely thrilled that our salon space designed from an empty shell has triumphed in this category. Patrick’s vision for the salon focused on creating a truly unique hairdressing experience unrivalled in the North West, a five star experience from beginning to end at surprisingly affordable prices.”The company are now in our new premises in the Riverside Retail Park, Letterkenny seven weeks and from the feedback they have received they are delighted that their clients are as happy with it as they are.“We as a team genuinely love coming to work every day and are delighted that our vision has been acknowledged by succeeding in this award and we look forward to enhancing our customer experience through our excellent customer service every day”. A simple glance in the shop front of this luxurious salon highlights exactly why Patrick Gildea Hairdressing was successful in this award category.There is no other hairdressing establishment that provides such a beautiful environment for their clients and staff. The fabulous interior exemplifies part of the experience which matches the high standard of hairdressing provided within. It’s hard to believe that this space was once an empty shell but now feels lived in with an amazing atmosphere.Check out www.patrickgildea.ie and like them on Facebook at www.facebook.com/patrickgildeahairdressingThe Friendly Business Awards is a flagship business program which recognizes the pivotal role small businesses play in the local community. The awards were held at The Radisson Hotel, Letterkenny on 18th August and were presented by JCI Donegal President Emma Boylan. PATRICK GILDEA’S STUNNING SALON SCOOPS DESIGN AWARD was last modified: August 21st, 2014 by StephenShare this:Click to share on Facebook (Opens in new window)Click to share on Twitter (Opens in new window)Click to share on LinkedIn (Opens in new window)Click to share on Reddit (Opens in new window)Click to share on Pocket (Opens in new window)Click to share on Telegram (Opens in new window)Click to share on WhatsApp (Opens in new window)Click to share on Skype (Opens in new window)Click to print (Opens in new window)
26Jan Pagel bill for parole hearings gets governor’s ceremonial signing Categories: Pagel News,Pagel Photos State Representative Dave Pagel, from Berrien Springs, joined Governor Rick Snyder this week for a ceremonial bill signing of his parole reform legislation. This bill corrected an injustice in the parole system for certain prisoners serving long-term sentences. Some of these prisoners were being unfairly denied access to the possibility of having their cases heard by the parole board, and Pagel’s legislation corrected this situation. “This bill is a common-sense improvement that allows all prisoners an equal chance at the possibility of parole hearings,” Representative Pagel said after the bill signing. “It allows our professionals on the parole board to carry out their responsibilities properly. All prisoners should be treated fairly.” While no prisoners will be granted parole based on this legislation, some that were being denied the possibility of parole hearings will now be able to have their cases considered by the parole board. Many have written to Representative Pagel expressing their appreciation for now having greater hope for the eventual possibility of receiving parole.#####
A Tuscaloosa family of 4 is recovering in the hospital after their home caught fire around noon Wednesday.“I was coming out of the house and the front room of my cousin’s trailer was engulfed in flames.” That’s when Antonio Dancer told WVUA 23 News reporter Chelsea Barton he risked his life to help his family.“All I knew to do was try to get in the trailer and get them out. I ran through the back door and when I was coming through the back door, they met me at the back door with the kids,” Dancer exclaimed.Family members have identified the family who lived inside this home and Quenton White, his fiance Ravin and their young boys Kingston and Preston. All four were transported to DCH Regional Medical Center, where they are thankfully only being treated for smoke inhalation.“It’s a blessing that everybody got out safe,” family member Denise Davis said. “My family is already going through a hard time. Out aunt passed today, so I am just thankful that everyone is okay,” she told WVUA 23.Tuscaloosa Fire and Rescue received the call to 3405 University Boulevard East minutes after noon on Wednesday.They responded immediately and had the fire under control and extinguished within minutes, but want this to be a reminder to everyone of how fast fires can spread.“It don’t take long at all,” Davis exclaimed. “Tragedy can happen quick. You only get one life and you can always get another home,” she said.Family members gave me clothing sizes for the family who lost their home.The adult male wears men’s pants in a size 36’32’, L/XL shirts and a size 9 shoe.The adult female wears women’s size 14 pants, M/L shirts and a size 9 shoe.The boys wear sizes 3t and 4t clothing and children’s size 7 shoes.If you’d like to donate to this family, please call ary at (205) 764 -2364.The cause of that fire is still under investigation.
Source:https://benthamscience.com/ Reviewed by James Ives, M.Psych. (Editor)Dec 17 2018Nanomedicine refers to field of science that uses nanotechnology for clinical operations. The use of nanoparticles (NPs) has specially been successful due to their structure. For example, NPs have the ability to cross biological barriers which boosts their effectiveness towards complicated drug delivery problems. This permeability allows NPs to reach biological targets such as brain cells, which would have been impossible by conventional drugs. Due to their effectiveness in this area, NPs have now been prioritized from simply being experimental tests compounds to be used as a workable solution for neurodegenerative disease (ND). NDs, such as Alzheimer’s disease and Parkinson’s disease are usually correlated with neuronal death, or in other words, the continuous structural and functional neuronal loss.Related StoriesNew therapy shows promise in preventing brain damage after traumatic brain injuryNeural pathways explain the relationship between imagination and willingness to helpPosterior parietal cortex plays crucial role in making decisions, research showsIn common ND treatment strategies, one of the hardest obstruction to overcome is low penetration of the drug through the central nervous system (CNS). One of the reasons for this problem is the Blood Brain Barrier (BBB) and Blood Cerebrospinal Fluid Barrier (BCSFB) which protect the brain from invading and unwanted substances. The barriers carry out their function with the help of multispecific transport proteins and detoxifying enzymes. Using nanoparticles opens up many possibilities to counter such obstacles in the NDs treatment as they are proven to effectively deliver drugs to the CNS. The research focuses on the modification of lipid nanoparticles for brain targeting to increase drug efficiency and ability to deliver different kinds of drugs.In conclusion, it has been difficult to establish which lipid nanoparticle, based on previous tests, was best for ND treatment since the administration route or animal models for each test were different. For the time being, researchers suggest that additional studies and tests are needed to propel research on CNS based drug delivery towards successful brain cell targeting.
Honda to unveil new compact gas-electric hybrid sedan This photo provided by General Motors shows the 2013 Cadillac CTS, a midsize sedan available for under $15,000. The 304-horsepower CTS is a solid pick in the used-car market. (Courtesy of General Motors Co. via AP) Citation: Edmunds recommends 15 used cars for under $15K (2018, January 24) retrieved 18 July 2019 from https://phys.org/news/2018-01-edmunds-cars-15k.html This photo provided by Lexus shows the 2014 Lexus CT 200h, a hybrid available in the used-car market for under $15,000. The small CT 200h offers a touch of luxury, plus an EPA rating of 42 mpg combined. (David Dewhurst Photography/Courtesy of Toyota Motor Sales U.S.A. via AP) This photo provided by Volvo shows the 2014 Volvo V60, a small wagon shoppers will find priced under $15,000. The V60 provides a comfortable interior, with the benefit of Volvo’s reputation for safety. (Courtesy of Volvo Cars of North America via AP) This photo provided by General Motors shows the 2013 Cadillac CTS, a midsize sedan available for under $15,000. The 304-horsepower CTS is a solid pick in the used-car market. (Courtesy of General Motors Co. via AP) © 2018 The Associated Press. All rights reserved. This photo provided by Honda shows the 2015 Honda Odyssey, a popular minivan now priced under $15,000. Plenty of family-friendly features make the Odyssey a sensible option for small and large families. (Courtesy of American Honda Motor Co. via AP) This photo provided by Mazda shows the 2015 Mazda CX-9, a full-size SUV available for less than $15,000. If the CX-5 is too small for your needs, the CX-9 is a step up in space and features. (David Dewhurst Photography/Courtesy of Mazda North American Operations via AP) If you want a three-row crossover, check out the 2009-2012 Ford Flex with its distinctive big-wagon styling. It’s one of the better-driving three-rows, with an available turbocharged V6 engine, lots of passenger space and cross-country roadtrip-worthy comfort. Another solid option is the 2010-2015 Mazda CX-9 . Its athletic road manners are complemented by comfortable seats, three usable rows and plenty of cargo capacity. Just note that its crash safety scores weren’t the best. This photo provided by Honda shows the 2015 Honda Civic sedan, a perennial favorite in the used-car market. This wasn’t the automaker’s strongest Civic model, but it’s still a great option for buyers shopping for a vehicle under $15,000. (Courtesy of American Honda Motor Co. via AP) This photo provided by Toyota shows the 2012 Toyota Camry Hybrid, which is available for less than $15,000. The Camry Hybrid offers a comfortable interior and ride, and it returns about 40 mpg. (Courtesy of Toyota Motor Sales U.S.A. via AP) TRUCKS AND VANSWhile there is no end of old Ford F-150s and Chevrolet Silverados available, our pick has to be the 2007-2013 Toyota Tundra . This rugged, durable truck offers a burly V8 that can tow up to 10,000 pounds. Unless you’re a patient bargain hunter, you might have to opt for a slightly higher-mileage Tundra, but we think the extra miles are worth it for such a capable truck. Buyers looking for something smaller should check out the Tundra’s popular little brother, the Tacoma.If you need to haul people rather than bricks, the 2011-2013 Honda Odyssey is your best bet. Compared to its predecessor, the redesigned 2011 Odyssey sports more interior space and offers more upgrades including a premium stereo, chilled storage box and rear-seat entertainment system. Pre-2011 Odysseys are great choices, too.EDMUNDS SAYS: No matter which vehicle you choose, remember to do your research to make sure you’re getting the best used car for your money. You’ll be able to find some cars on our list with certified pre-owned warranties, but checking vehicle history reports and having an independent inspection done will give you added peace of mind. Depreciation may be the bane of new-car buyers, but it’s also the reason so many shoppers buy used. We scoured our annual Edmunds New Car Buying Guides from years past to see what cars we loved back in the day can now be had for $15,000 or less. For each vehicle, we’ve provided a range of years offering the best selection and value. In certain cases, getting an even older model is a viable option, too. This photo provided by Honda shows the 2015 Honda Civic sedan, a perennial favorite in the used-car market. This wasn’t the automaker’s strongest Civic model, but it’s still a great option for buyers shopping for a vehicle under $15,000. (Courtesy of American Honda Motor Co. via AP) This photo provided by Mazda shows the 2015 Mazda CX-5, a small SUV available in the used-car market for less than $15,000. The Mazda CX-5 is not only practical, but it also provides sporty handling on the road. (Courtesy of Mazda North American Operations via AP) This photo provided by Mazda shows the 2014 Mazda 6, a midsize sedan available in the used-car market. The Mazda 6 offers a sporty look and feel for less than $15K. (Courtesy of Mazda North American Operations via AP) This photo provided by Volkswagen shows the 2014 Volkswagen Golf GTI, a small car available for less than $15,000. The popular GTI offers the convenience and versatility of a hatchback. (Courtesy of Volkswagen of America via AP) This photo provided by Ford shows the 2011 Ford Flex, a full-size SUV available in the used-car market for less than $15,000. The Flex rivals most minivans for passenger space, with three rows of seating. (Sam VarnHagen/Courtesy of Ford Motor Co. via AP) SMALL CARSThe 2013-2015 Honda Civic is a great place to begin our list. We didn’t like this generation Civic much when it came out for 2011, but Honda improved it dramatically by 2013. It’s spacious and easy to live with, and it offers quite a few technology options. It’s also available as a fuel-sipping hybrid or as the fun-to-drive 205-horsepower Civic Si.For more luxurious comfort and safety, check out the 2011-2014 Volvo S60 sedan and the V60 wagon . This Volvo has front seats perfect for long hauls, and the available engines are surprisingly peppy. If you value performance over practicality, try the 2009-2012 BMW 1 Series . It never sold in big numbers, but this littlest BMW provides lots of fun in either coupe or convertible guise.Finally, the 2011-2014 Volkswagen GTI combines fun with hatchback practicality. The GTI has always been one of our favorites thanks to its refined driving experience and near-luxury interior.MIDSIZE CARSThe 2011-2014 Cadillac CTS marked a turning point for Cadillac, challenging European competitors with its quality, comfort and driving precision. Look for CTS models with the 3.6-liter direct-injected V6, which puts out 304 horsepower without sacrificing fuel economy. This photo provided by Honda shows the 2015 Honda Odyssey, a popular minivan now priced under $15,000. Plenty of family-friendly features make the Odyssey a sensible option for small and large families. (Courtesy of American Honda Motor Co. via AP) This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. Explore further The 2011-2014 Acura TSX is a good all-arounder that didn’t stand out from the crowd when new. But for under $15,000, it makes a compelling alternative to a used Accord. Look for one with the Ttechnology package to get the rearview camera and upgraded sound and navigation systems.For something a little newer, try the 2014-2016 Mazda 6 . Like many Mazdas, a used Mazda 6 can be a little hard to find, but its handling is among the best in the class. An upscale interior, plenty of backseat room, and an easy-to-use technology interface round out the appeal of this late-model midsize car.SUVsThe safe bet for used SUVs is the 2012-2016 Honda CR-V . It’s a practical, reliable compact SUV, if not the most exciting to drive. In 2015, the CR-V was updated with a more fuel-efficient engine. We also recommend the 2013-2015 Mazda CX-5 , especially in Touring or Grand Touring trim. The CX-5 has an upscale interior and excellent handling, returns good fuel economy, and is just as practical as competitors. HYBRIDSThere’s no shortage of Toyota Priuses around, but we prefer the 2012-2015 Toyota Camry Hybrid . It provides reasonable acceleration for a hybrid, along with a comfortable interior and ride, and it returns about 40 mpg. It’s not quite as efficient as the Prius, but it’s nicer to live with day to day.We’re going to break one of our rules for this next one: We never featured the 2011-2015 Lexus CT 200h in an Edmunds Buying Guide, but it’s a great used pick. New, it fell short of its promise of being a sporty hybrid, but as a Prius alternative it’s an appealing proposition. It’s more luxurious and better to drive and returns 42 mpg in combined (city and highway) driving. This photo provided by Toyota shows the 2010 Toyota Tundra, one option for buyers looking for a used truck under $15,000. The durable Tundra offers a V8 that can tow up to 10,000 pounds. (David Dewhurst/Courtesy of Toyota Motor Sales U.S.A. via AP) This photo provided by American Honda Motor Co. shows the 2014 Acura TSX, a midsize sedan that can be found for less than $15,000. The TSX is a good choice for buyers looking for optional tech features. (Courtesy of American Honda Motor Co. via AP) This photo provided by BMW shows the 2012 BMW 1 Series, a sports car available in the used-car market for less than $15,000. The 1 Series is available in both coupe and convertible models. (Daniel Kraus/Courtesy of BMW of North America via AP)
Explore further © 2018 AFP This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. Sales of the Chevy Cruze dropped 32 percent in the last four years as Americans have shunned small cars in favor of SUVs, prompting General Motors to cut back on production Sales of diesel cars in Germany drop after court permits ban General Motors will cut more than 1,000 jobs in the US tied to production of sedans that are in low demand, the automaker said Friday. The cuts will affect GM’s factory in Lordstown, Ohio, where the biggest US automaker produces the Chevrolet Cruze.Sales of the vehicle have dropped 32 percent in the last four years, the company said, part of a broader trend in the US that has seen consumers ignore small cars in favor of sports utility vehicles and larger “crossover” cars amid low gasoline prices and a recovering economy.The Ohio plant, which currently employs around 3,000 people, has built cars in two shifts. The ramp-down follows an “historic” shift in the market, a GM spokeswoman said in an email.”As we look at the market for compact cars in 2018 and beyond, we believe a more stable operating approach to match market demand is a one-shift schedule,” the spokeswoman said. “Consequently, we will suspend the second shift of production at Lordstown late in the second quarter of 2018.”GM notified regulators that up to 1,500 jobs could be impacted by the move, with the final number to be determined in the coming weeks. Last year, GM sold 150,000 Chevy Cruze cars in the US, all produced at Lordstown. Since the start of 2018, sales of the vehicle have dropped 28 percent, according to auto consultancy and data firm Autodata.In total, sales of small US cars have fallen 13.2 percent since the start of 2018, while sales of large cars have risen seven percent. Citation: GM to cut more than 1,000 US jobs tied to small cars (2018, April 13) retrieved 18 July 2019 from https://phys.org/news/2018-04-gm-jobs-tied-small-cars.html